abstract：BACKGROUND:In recent years photopheresis, an extracorporeal form of photochemotherapy using psoralen and ultraviolet A irradiation of leucocytes, has been claimed to be an effective form of immunomodulation. AIM:To evaluate its effect in type 1 diabetes we performed a double blind, controlled study using placebo table...

journal_title：Archives of disease in childhood

authors： Ludvigsson J,Samuelsson U,Ernerudh J,Johansson C,Stenhammar L,Berlin G

更新日期：2001-08-01 00:00:00

abstract：:In a prospective study, 60% of admissions to an academic hospital were infected with HIV. HIV infected children were younger, less likely to have been referred, more likely to have pneumonia and candidiasis, and had more health service attendances. This impact may be alleviated by appropriate primary and secondary lev...

journal_title：Archives of disease in childhood

authors： Pillay K,Colvin M,Williams R,Coovadia HM

更新日期：2001-07-01 00:00:00

abstract：OBJECTIVE:To study the effect of body composition on average daily metabolic rate (ADMR) and basal metabolic rate (BMR) in adolescence, and to examine current BMR prediction equations. STUDY:Dutch adolescents were pooled with previously reported American and British subjects (n = 90 overall). BMR and ADMR were analyse...

journal_title：Archives of disease in childhood

authors： van Mil EG,Westerterp KR,Kester AD,Saris WH

更新日期：2001-07-01 00:00:00

abstract：:We describe a 21 month old male infant who presented with failure to thrive associated with severe hypokalaemia and metabolic acidosis, together with hypomagnesaemia. Evaluation revealed marked renal and probable faecal potassium wasting, distal renal tubular acidosis, mild urinary magnesium wasting, and a normal gast...

journal_title：Archives of disease in childhood

authors： Simpson AM,Schwartz GJ

更新日期：2001-06-01 00:00:00

abstract：AIMS:To examine the disease burden and epidemiology of community acquired rotavirus gastroenteritis in Austrian children treated in a paediatric practice. METHODS:A prospective, population based, multicentre study in four paediatric practices and two children's hospitals (Innsbruck and Leoben). Children

journal_title：Archives of disease in childhood

authors： Frühwirth M,Karmaus W,Moll-Schüler I,Brösl S,Mutz I

更新日期：2001-05-01 00:00:00

abstract：AIM:To investigate the safety of bronchoscopy and endobronchial biopsy in children with difficult asthma, and discuss the ethical issues associated with the procedure. METHODS:A three year prospective observational study was performed in two tertiary paediatric respiratory centres specialising in the management of chi...

journal_title：Archives of disease in childhood

authors： Payne D,McKenzie SA,Stacey S,Misra D,Haxby E,Bush A

更新日期：2001-05-01 00:00:00

abstract：:In a prospective follow up of 116 high risk infants, a 24 hour behavioural chart on seven consecutive days was analysed at seven and 12 weeks of age. Of children who manifested atopic disease at 2 years, 44/116 (38%), had shown significantly more fussing during the seventh, and colic type cry during the twelfth week t...

journal_title：Archives of disease in childhood

authors： Kalliomäki M,Laippala P,Korvenranta H,Kero P,Isolauri E

更新日期：2001-04-01 00:00:00

abstract：:A CAUSAL ASSOCIATION BETWEEN MEASLES: mumps-rubella (MMR) vaccine and idiopathic thrombocytopenic purpura (ITP) was confirmed using immunisation/hospital admission record linkage. The absolute risk within six weeks of immunisation was 1 in 22 300 doses, with two of every three cases occurring in the six week post-immu...

journal_title：Archives of disease in childhood

authors： Miller E,Waight P,Farrington CP,Andrews N,Stowe J,Taylor B

更新日期：2001-03-01 00:00:00

abstract：:Non-accidental injury should be suspected and excluded in any infant found to have intracranial and retinal haemorrhage of unknown aetiology. This can be a sensitive issue for both medical staff and parents. We present a case in which the underlying cause of intracranial and retinal haemorrhage was fibromuscular dyspl...

journal_title：Archives of disease in childhood

authors： Currie AD,Bentley CR,Bloom PA

更新日期：2001-03-01 00:00:00

abstract：AIMS:To develop and implement an evidence based guideline for the treatment of acute asthma using a metered dose inhaler and spacer combination. METHODS:Defined strategies were used for the development and implementation of a guideline, assessed by a prospective, descriptive, study using notes review, and patient, nur...

journal_title：Archives of disease in childhood

authors： Powell CV,Maskell GR,Marks MK,South M,Robertson CF

更新日期：2001-02-01 00:00:00

abstract：AIMS:To investigate how parents report children's respiratory sounds on video compared to a clinical "gold standard". METHODS:Five clinicians agreed on 10 video clips of children with audible breathing. These responses were the "gold standard". The clips were shown to parents of children: (a) with asthma/wheeze; (b) w...

journal_title：Archives of disease in childhood

authors： Cane RS,McKenzie SA

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:Cerebral palsy is the commonest cause of severe physical disability in childhood. For many years treatment has centred on the use of physiotherapy and orthotics to overcome the problems of leg spasticity, which interferes with walking and can lead to limb deformity. Intramuscular botulinum toxin (BT-A) offer...

journal_title：Archives of disease in childhood

authors： Ubhi T,Bhakta BB,Ives HL,Allgar V,Roussounis SH

更新日期：2000-12-01 00:00:00

abstract：AIM:To determine the incidence of hypocalcaemia in critically ill children with meningococcal disease. METHODS:In a prospective cohort study, 70 of 80 patients admitted consecutively with a clinical diagnosis of meningococcal disease to intensive care had measurements of total and ionised calcium on admission. Paratho...

journal_title：Archives of disease in childhood

authors： Baines PB,Thomson AP,Fraser WD,Hart CA

更新日期：2000-12-01 00:00:00

abstract：:The characteristics of nine children with community acquired pneumonia with evidence of Streptococcus pneumoniae and Mycoplasma pneumoniae coinfection are described. ...

journal_title：Archives of disease in childhood

authors： Toikka P,Juvén T,Virkki R,Leinonen M,Mertsola J,Ruuskanen O

更新日期：2000-11-01 00:00:00

abstract：AIM:To measure drug adherence in children with mild asthma receiving long term prophylactic treatment. METHODS:Double blind randomised placebo controlled trial. Patients received inhaled budesonide 100 microg or 200 microg daily, or placebo for 27 months. All participants were asked to inhale medication or placebo fro...

journal_title：Archives of disease in childhood

authors： Jónasson G,Carlsen KH,Mowinckel P

更新日期：2000-10-01 00:00:00

abstract：:Popliteal artery entrapment syndrome (PAES) is a rare but potentially limb threatening anatomical anomaly occurring predominantly in young adults. We report a case of a 14 year old boy who presented with limb threatening ischaemia requiring urgent surgery. The pathology, presentation, and management are discussed. ...

journal_title：Archives of disease in childhood

authors： Chan CW,Wilson JI,Myatt A,Roberts PN

更新日期：2000-10-01 00:00:00

abstract：AIMS:To determine whether the British 1990 growth charts are valid for cross sectional and longitudinal use in primary school children. METHODS:A total of 694 children aged 7-10 years from 10 Leeds primary schools were weighed and measured annually over three years by an expert auxologist. SD scores were calculated us...

journal_title：Archives of disease in childhood

authors： Rudolf MC,Cole TJ,Krom AJ,Sahota P,Walker J

更新日期：2000-10-01 00:00:00

abstract：AIM:To document the impact that rapid increases in HIV infection in hospitalised children at Chris Hani Baragwanath Hospital has had on in-hospital mortality. METHODS:Hospital discharge summaries from January 1992 to the end of 1996 were reviewed. RESULTS:There were 20 733 admissions in the five year period; 7985 (39...

journal_title：Archives of disease in childhood

authors： Zwi K,Pettifor J,Soderlund N,Meyers T

更新日期：2000-09-01 00:00:00

abstract：BACKGROUND:Congenital facial palsy (CFP) is clinically defined as facial palsy present at birth. It is associated with considerable disfigurement and causes functional and emotional problems for the affected child. The aetiology of the majority of cases however, remains elusive. AIMS:To investigate the role of a neuro...

journal_title：Archives of disease in childhood

authors： Jemec B,Grobbelaar AO,Harrison DH

更新日期：2000-09-01 00:00:00

abstract：METHODS:A total of 43 children with neurological signs and symptoms were enrolled in the study. All children were suspected of having meningitis, and lumbar punctures were performed. Human herpesvirus 6 (HHV-6) and HHV-7 DNA was detected in cerebrospinal fluid (CSF) and peripheral blood mononuclear cells (PBMC) by nest...

journal_title：Archives of disease in childhood

authors： Yoshikawa T,Ihira M,Suzuki K,Suga S,Matsubara T,Furukawa S,Asano Y

更新日期：2000-08-01 00:00:00

abstract：BACKGROUND:Faecal impaction is frequently observed in children with chronic constipation. The term megarectum is often used to describe this finding. AIM:To evaluate rectal functioning and rectal measures in constipated children with a filled rectum, in order to define the terms faecal impaction, enlarged rectum, and ...

journal_title：Archives of disease in childhood

authors： van der Plas RN,Benninga MA,Staalman CR,Akkermans LM,Redekop WK,Taminiau JA,Buller HA

更新日期：2000-07-01 00:00:00

abstract：:A picture archiving and communication system (PACS) is a computerised means of replacing the roles of conventional radiological film. This review describes the Hammersmith PACS, and discusses the advantages and disadvantages of PACS systems. ...

journal_title：Archives of disease in childhood

authors： Strickland NH

更新日期：2000-07-01 00:00:00

abstract：AIM:To determine the outcome and identify predictive factors in children with psychogenic non-epileptic seizures (PNES). METHOD:The biographies of 35 children with PNES, attending a tertiary paediatric neurology centre, were reviewed. RESULTS:Thirty five children attending the department between 1987 and 1997 were ev...

journal_title：Archives of disease in childhood

authors： Irwin K,Edwards M,Robinson R

更新日期：2000-06-01 00:00:00

abstract：:The role of inflammation in adult asthma is well known, involving a cascade of immunological stimulation in which mast cells and eosinophils play pivotal roles. However, the assessment of airway inflammation in children is more difficult as the invasive methods used in adults cannot ethically be used for this purpose ...

journal_title：Archives of disease in childhood

authors： Chedevergne F,Le Bourgeois M,de Blic J,Scheinmann P

更新日期：2000-06-01 00:00:00

abstract：AIMS:To investigate socioeconomic inequalities in the risk of congenital anomalies, focusing on risk of specific anomaly subgroups. METHODS:A total of 858 cases of congenital anomaly and 1764 non-malformed control births were collected between 1986 and 1993 from four UK congenital malformation registers, for the purpo...

journal_title：Archives of disease in childhood

authors： Vrijheid M,Dolk H,Stone D,Abramsky L,Alberman E,Scott JE

更新日期：2000-05-01 00:00:00

abstract：:An usually high rate of both tuberculosis infection and active disease is reported in 11 of 38 nursery children in contact with a case of smear positive pulmonary tuberculosis, emphasising the susceptibility of young children to this disease. This report also underlines some important principles in case finding and di...

journal_title：Archives of disease in childhood

authors： Milburn HJ,Gibilaro J,Atkinson H,Heathcock R

更新日期：2000-05-01 00:00:00

abstract：BACKGROUND:Sweat testing procedures are perceived to vary widely. AIM:To evaluate variability in sweat collection, analysis, and interpretation. METHODS:Questionnaire responses from 30 self selected centres: 15 paediatric centres, and 15 district general hospitals. RESULTS:Centres carried out 30-400 tests per year (...

journal_title：Archives of disease in childhood

authors： Kirk JM

更新日期：2000-05-01 00:00:00

abstract：:Trigeminal neuralgia (TN) is a frequent cause of paroxysmal facial pain and headache in adults. Glossopharyngeal neuralgia (GPN) is less common, but can cause severe episodic pain in the ear and throat. Neurovascular compression of the appropriate cranial nerve as it leaves the brain stem is responsible for the sympto...

journal_title：Archives of disease in childhood

authors： Childs AM,Meaney JF,Ferrie CD,Holland PC

更新日期：2000-04-01 00:00:00

abstract：OBJECTIVE:To assess the accuracy of parental recall of birth weight in a British population and to investigate whether social class and age of the child significantly influence the accuracy of recalled birth weight. METHODS:A questionnaire was given to parents whose children were participating in a blood pressure stud...

journal_title：Archives of disease in childhood

authors： O'Sullivan JJ,Pearce MS,Parker L

更新日期：2000-03-01 00:00:00

abstract：:Fever is a common symptom of childhood illness, and much time and effort is spent in the pursuit of reducing high temperature. Although antipyretic drugs are the main form of treatment, this report considers the part that physical treatments might play in reducing the temperature of febrile children. Such treatments i...

journal_title：Archives of disease in childhood

authors： Purssell E

更新日期：2000-03-01 00:00:00

abstract：BACKGROUND:Pneumocystis carinii is an important pathogen in immunodeficiency but may be an unrecognised cause of respiratory compromise. OBJECTIVES:To ascertain the incidence of P carinii pneumonia (PCP) at presentation of severe combined immunodeficiency (SCID), whether it had been diagnosed, and the effect of treatm...

journal_title：Archives of disease in childhood

authors： Berrington JE,Flood TJ,Abinun M,Galloway A,Cant AJ

更新日期：2000-02-01 00:00:00

abstract：AIMS:To test the hypothesis that oxygen free radicals are mediators of excessive protein permeability in steroid responsive nephrotic syndrome. DESIGN:Case control study. SUBJECTS: PATIENTS:20 children with steroid responsive nephrotic syndrome; controls: 20 children admitted for elective surgery. SETTING:The paedi...

journal_title：Archives of disease in childhood

authors： Kinra S,Rath B,Kabi BC

更新日期：2000-01-01 00:00:00

abstract：:Simplified guidelines for the emergency care of children have been developed to improve the triage and rapid initiation of appropriate emergency treatments for children presenting to hospitals in developing countries. The guidelines are part of the effort to improve referral level paediatric care within the World Heal...

journal_title：Archives of disease in childhood

authors： Gove S,Tamburlini G,Molyneux E,Whitesell P,Campbell H

更新日期：1999-12-01 00:00:00

abstract：:This paper reviews the diagnostic features of cluster headache-like disorder and describes its presentation in childhood. Case note summaries of patients with this condition are presented in the context of a brief summary of the literature. Four patients (two girls; aged 12 to 15 years) with cluster headache-like diso...

journal_title：Archives of disease in childhood

authors： McNabb S,Whitehouse W

更新日期：1999-12-01 00:00:00

abstract：AIM:To compare the growth patterns of breast fed and formula fed Italian infants in the first 12 months of life using World Health Organisation (WHO) reference data. METHODS:The growth patterns of 73 breast fed infants (36 male, 37 female) and 65 formula fed infants (35 male, 30 female) were compared. Solid foods were...

journal_title：Archives of disease in childhood

authors： Agostoni C,Grandi F,Giannì ML,Silano M,Torcoletti M,Giovannini M,Riva E

更新日期：1999-11-01 00:00:00

abstract：OBJECTIVE:To study the epidemiology of pyridoxine dependent seizures and other forms of pyridoxine responsive seizures. DESIGN:Monthly notifications to the British Paediatric Surveillance Unit over two years. Questionnaire follow up. SETTING:UK and the Republic of Ireland. PATIENTS:Children aged 15 years or younger ...

journal_title：Archives of disease in childhood

authors： Baxter P

更新日期：1999-11-01 00:00:00

abstract：:349 Maasai children younger than 6 years old were randomised by alternate household to drink water either left in plastic bottles exposed to sunlight on the roof of the house or kept indoors (control). The trial was run in Maasai by Maasai community elders. Children drinking solar disinfected water had a significantly...

journal_title：Archives of disease in childhood

authors： Conroy RM,Meegan ME,Joyce T,McGuigan K,Barnes J

更新日期：1999-10-01 00:00:00

abstract：BACKGROUND:The passage of hard stools is significantly more common in formula fed infants than breast fed infants and this might be the result of differences in fat absorption between breast and formula fed infants. Experimental studies indicate that long chain polyunsaturated fatty acids (LCPUFAs) might influence fat ...

journal_title：Archives of disease in childhood

authors： Forsyth JS,Varma S,Colvin M

更新日期：1999-09-01 00:00:00

abstract：AIM:To determine the frequency of use of complementary treatment and measure its impact on clinical outcomes in a hospitalised general paediatric population. METHODS:A population based random sample of children admitted to the general paediatric service at a metropolitan children's hospital in Auckland, New Zealand fr...

journal_title：Archives of disease in childhood

authors： Armishaw J,Grant CC

更新日期：1999-08-01 00:00:00

abstract：:Blood pressure (BP) values and the phenomenon of tracking were evaluated in a group of 481 schoolchildren over a nine year period starting at age 6 years. BP values were obtained yearly by taking the mean of two measurements at one visit, measurements were taken by only two observers during the study. For both systoli...

journal_title：Archives of disease in childhood

authors： Sánchez-Bayle M,Muñoz-Fernández MT,González-Requejo A

更新日期：1999-08-01 00:00:00